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Bimetinib 15mg Alibimetini 15mg/tablet 90 tablets/bottle Combined Pharmaceutical [Logistics aging 7-14 days]
Bimetinib is a kinase inhibitor indicated for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation and for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) with a BRAF V600E mutation.
Medication Safety Tips
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- Contraindications
- 【Precautions】
New primary malignancies, both cutaneous and non-cutaneous: Patients should be monitored for new malignancies before, during, and after discontinuation of treatment.
Cardiomyopathy: Left ventricular ejection fraction (LVEF) is assessed before treatment, 1 month after treatment, and every 2-3 months after treatment.
Venous thromboembolism: Deep vein thrombosis and pulmonary embolism may occur.
Ocular toxicity: Ophthalmologic assessments are performed regularly and any visual impairment is evaluated.
Interstitial lung disease (ILD): Evaluate for new or progressive unexplained pulmonary symptoms to determine the likelihood of interstitial lung disease.
Hepatotoxicity: Monitor indicators of liver function as clinically necessary before and during treatment with bimetinib and icofenib.
Rhabdomyolysis: Regularly monitor creatine phosphokinase and creatinine levels as clinically indicated.
Bleeding: Serious bleeding events may occur in patients treated with bimetinib and icofenib.
Embryo-fetal toxicity: May cause harm to the fetus. Inform women of their fertility potential of the potential risks to the fetus and recommend the use of effective contraception. - Medication risks
- [Adverse reactions] Fatigue, nausea, diarrhea, musculoskeletal pain, vomiting, abdominal pain, visual impairment, constipation, dyspnea, rash, and cough.
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