Tivozanib 0.89 mg Tivozanib capsules 0.89 mg × 21 capsules/box

Medication Safety Tips

Use this product according to its instructions, medical advice, and your health needs. Shipping is arranged after payment once the order meets dispatch requirements.

Contraindications

Warnings and Precautions
• Blood Pressure and Blood Pressure Crisis: Control blood pressure before starting LuciTivo. Monitor Blood Pressure and treat as needed. For patients with persistent blood pressure despite anti-Blood Pressure medication, reduce the dose of LuciTivo.
• Heart Failure: Signs or symptoms of heart failure are monitored throughout LuciTivo treatment.
• Cardiac ischemia and arterial thromboembolic events: Patients at increased risk for these events are closely monitored. In case of severe thromboembolic events such as myocardial infarction and stroke, permanently discontinue LuciTivo.
• Venous thromboembolic events: Patients at increased risk for these events are closely monitored. In case of severe venous thromboembolic events, permanently discontinue LuciTivo.
• Bleeding events: Patients at risk of bleeding or with a history of bleeding are closely monitored.
• Proteinuria: monitored throughout LuciTivo treatment. For moderate to severe proteinuria, reduce the dose or temporarily interrupt LuciTivo treatment.
• Thyroid dysfunction: monitored before starting LuciTivo and throughout treatment.
• Risk of impaired wound healing: discontinue use of LuciTivo at least 24 days prior to elective surgery. Do not use for at least 2 weeks after major surgery and full wound healing. The safety of returning to LuciTivo after resolution of wound healing complications has not been determined.
• Reversible Posterior Leukoencephalopathy Syndrome (RPLS): In case of signs or symptoms of RPLS, discontinue use of LuciTivo.
• Embryo-fetal toxicity: May cause fetal harm. Inform the patient of the potential risks to the fetus and use effective contraception.

Medication risks

Adverse Reactions
The most common (≥ 20%) adverse reactions were fatigue, blood pressure, diarrhea, decreased appetite, nausea, dysphoria, hypothyroidism, cough, and stomatitis, and the most common grade 3 or 4 laboratory abnormalities (≥ 5%) were decreased sodium, increased lipase, and decreased phosphate.