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Encorafenib capsules 75 mg/capsule, 90 capsules/box
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- Contraindications
- Warnings and Precautions
• New primary malignancies, both cutaneous and noncutaneous: may occur. Malignant tumors are monitored and dermatologically evaluated before, during, and after treatment discontinuation.
• Tumorigenesis in BRAF wild-type tumors: Use of BRAF inhibitors may increase cell proliferation.
• Bleeding: Serious bleeding events may occur.
• Uveitis: Perform regular eye assessments and check for any visual impairments.
• Prolonged QT interval: electrolytes are monitored before and during treatment. Correcting electrolyte abnormalities and controlling cardiac risk factors for prolonged QT intervals. When the QTc is 500 milliseconds or more, stop using LuciEncor.
• Embryo-fetal toxicity: May cause harm to the fetus. Women of childbearing potential are advised to be aware of the potential risks to the fetus and to use effective non-hormonal methods of contraception. - Medication risks
- Adverse Reactions
The most common adverse effects (> 25%) of LuciEncor in combination with binimetinib are fatigue, nausea, vomiting, abdominal pain, and joint pain.
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